UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549


FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934

Date of Report: August 10, 2015
(Date of earliest event reported)

Theravance Biopharma, Inc.
(Exact name of registrant as specified in its charter)

Cayman Islands
(State or other jurisdiction
of incorporation)
001-36033
(Commission File Number)
EIN 98-1226628
(IRS Employer
Identification Number)

PO Box 309, Ugland House, South Church Street, George Town, Grand Cayman, Cayman Islands
(Address of principal executive offices)
  KY1-1104
(Zip Code)

650-808-6000
(Registrant's telephone number, including area code)

Not Applicable
(Former Name or Former Address, if changed since last report)


Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):
o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Item 9.01. Financial Statements and Exhibits

(d) Exhibits
            99.1       Press Release dated August 10, 2015


SIGNATURE

      Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.


Dated: August 10, 2015
THERAVANCE BIOPHARMA, INC.

By:  /s/                    
     
     


Exhibit Index
Exhibit No. Description
99.1 Press Release dated August 10, 2015

Theravance Biopharma, Inc. Reports Second Quarter 2015 Financial Results and Provides Business Update

DUBLIN, IRELAND -- (Marketwired - August 10, 2015) - Theravance Biopharma, Inc. (NASDAQ: TBPH) ("Theravance Biopharma" or the "Company") today reported financial results for the second quarter ending June 30, 2015. Revenue for the second quarter of 2015 was $7.1 million. Net loss for the second quarter of 2015 was $47.6 million, or $1.42 per share. Cash, cash equivalents, and marketable securities, excluding restricted cash, totaled $228.8 million as of June 30, 2015.

Rick E Winningham, Chairman and Chief Executive Officer, commented: "In the first half of 2015, we have focused on executing our strategies to advance TD-4208 to a registrational Phase 3 program, creating an acute care commercial organization in the U.S., while positioning VIBATIV® (telavancin) as an important treatment for patients with life-threatening infections, and advancing our two high-value research programs towards the clinic. We are pleased with the progress achieved with our programs to date, and believe we have multiple opportunities to generate value across our entire portfolio."

Continued Mr. Winningham: "Building VIBATIV into a global brand is a key component of our Company's strategy to create a portfolio of high-value, innovative medicines that create value for both patients and shareholders. We are pleased by our achievements in establishing revenue-generating partnerships for VIBATIV outside the U.S. and the 66% quarter-over-quarter gain in VIBATIV U.S. net sales from the first quarter to the second quarter. We are also pleased with the underlying fundamentals we saw in the second quarter, including formulary wins, sales in new accounts and increased volume overall. In a relatively short period, we have created a national acute care focused organization staffed with excellent sales and medical professionals, and we remain on track to complete the sales force expansion to 50 representatives late in the third quarter. However, some recent issues have caused us to reduce our projected U.S. sales ramp for VIBATIV in the second half of 2015. We are working aggressively to address these issues, which include a greater percentage of our sales being made to Public Health Service institutions at a much lower price point, as mandated by the federal government, and the integration of new representatives into our sales force. While we believe it is prudent to reduce our full-year U.S. net sales guidance for VIBATIV, our outlook on the product's commercial potential remains quite positive. We remain committed to the ongoing clinical and commercial development of VIBATIV to serve physicians who treat life-threatening infections. Going forward, we intend to report on all VIBATIV-related revenues, including U.S. net sales, revenue from ex-U.S. sales, and sales and milestones generated from our ex-U.S. partnerships, which we believe more accurately reflect the overall value VIBATIV contributes to our Company."

Second-Quarter Summary and Business Update

Financial Results

Revenue

Total revenue for the second quarter of 2015 totaled $7.1 million. Total revenue consisted of net product sales of VIBATIV® (telavancin) of $2.1 million, an increase of $0.8 million or 66% over the prior quarter, and revenue from VIBATIV-related collaborative arrangements of $5.0 million. Revenue from collaborations included a $3.0 million upfront payment from SciClone Pharmaceuticals for execution of a development and commercialization agreement for VIBATIV in China and a $2.0 million regulatory milestone payment from R-Pharm for marketing approval of VIBATIV in Russia.

Cost of Goods Sold

Cost of goods sold for the second quarter of 2015 totaled $0.5 million.

Research and Development (R&D) Expenses

R&D expenses for the second quarter of 2015 decreased to $30.4 million compared to $46.3 million for the same period in 2014. The decrease was primarily due to lower costs associated with non-recurring long-term retention and incentive awards that were granted in 2011 and a decrease in program-related net expense due to the reimbursement of expenses associated with the Mylan TD-4208 collaboration. Total R&D share-based compensation expense was $6.8 million in the second quarter of 2015.

Selling, General and Administrative (SG&A) Expenses

SG&A expenses for the second quarter of 2015 were $21.5 million compared with $13.1 million for the same period in 2014. The increase was primarily due to costs associated with VIBATIV commercialization. Total share-based compensation expense in SG&A was $7.8 million in the second quarter of 2015.

Cash, Cash Equivalents and Marketable Securities

Cash, cash equivalents and marketable securities, excluding restricted cash, totaled $228.8 million as of June 30, 2015.

Receivables from Collaborative Arrangements

Receivables from collaborative arrangements totaled $25.5 million as of June 30, 2015, and includes $23.0 million in receivables associated with Mylan collaboration.

2015 Financial Guidance

The Company is revising 2015 U.S. net sales guidance for VIBATIV and establishing updated guidance that will include the impact of VIBATIV-related revenues worldwide. 2015 total revenue related to VIBATIV is expected to be in the range of $15 million to $18 million, with the majority of the revenue coming from net product sales in the U.S., which are now expected to be in range of $9 million to $12 million. The Company's non-GAAP operating loss guidance for the full-year of 2015 has remained unchanged at $120 million to $130 million. Non-GAAP operating loss guidance includes all revenues and costs and expenses from operations, excluding share-based compensation expense.

Basis of Presentation

On June 1, 2014, Theravance separated its late-stage respiratory assets partnered with GSK from its biopharmaceutical operations by transferring its discovery, development and commercialization operations (the "Biopharmaceutical Business") and contributing $393.0 million of cash, cash equivalents and marketable securities into its then wholly-owned subsidiary Theravance Biopharma. On June 2, 2014, Theravance made a pro rata dividend distribution to its stockholders of record on May 15, 2014 of one ordinary share of Theravance Biopharma for every three and one half shares of Theravance common stock outstanding on the record date (the "Spin-Off"). The Spin-Off resulted in Theravance Biopharma operating as an independent, publicly-traded company. Prior to June 2, 2014, Theravance was the parent for the Biopharmaceutical Business.

The financial statements of Theravance Biopharma for periods prior to the Spin-Off were derived from Theravance's historical consolidated financial statements, with expenses allocated through a specific identification basis or another reasonable allocation methodology. As such, the financial information included herein for periods prior to the Spin-Off may not necessarily reflect the financial profile of what Theravance Biopharma would have been had it been an independent, publicly traded company during those periods.

Conference Call Today at 5:00 pm ET

Theravance Biopharma will hold a conference call today at 5:00 pm EDT to discuss its second quarter 2015 financial results. To participate in the live call by telephone, please dial (855) 296-9648 from the U.S., or (920) 663-6266 for international callers. Those interested in listening to the conference call live via the internet may do so by visiting Theravance Biopharma's website at www.theravance.com, under the Investor Relations section, Presentations and Events. To listen to the live call via the internet, please go to the website 15 minutes prior to its start to register, download, and install any necessary audio software.

A replay of the conference call will be available on Theravance Biopharma's website for 30 days through September 10, 2015. An audio replay will also be available through 11:59 pm EDT on August 17, 2015 by dialing (855) 859-2056 from the U.S., or (404) 537-3406 for international callers, and entering confirmation code 94608507.

About Theravance Biopharma

The mission of Theravance Biopharma (NASDAQ: TBPH) is to create value from a unique and diverse set of assets: an approved product; a development pipeline of late-stage assets; and a productive research platform designed for long-term growth.

Our pipeline of internally discovered product candidates includes potential best-in-class opportunities in underserved markets in the acute care setting, representing multiple opportunities for value creation. VIBATIV® (telavancin), our first commercial product, is a once-daily dual-mechanism antibiotic approved in the U.S., Europe and certain other countries for certain difficult-to-treat infections. TD-4208 is an investigational long-acting muscarinic antagonist (LAMA) being developed as a potential once-daily, nebulized treatment for COPD. Axelopran (TD-1211) is an investigational potential once-daily, oral treatment for opioid-induced constipation (OIC). Our earlier-stage clinical assets represent novel approaches for potentially treating diseases of the lung and gastrointestinal tract and infectious disease. In addition, we have an economic interest in future payments that may be made by GlaxoSmithKline plc pursuant to its agreements with Theravance, Inc. relating to certain drug development programs, including the combination of fluticasone furoate, umeclidinium, and vilanterol (the "Closed Triple").

With our successful drug discovery and development track record, commercial infrastructure, experienced management team and efficient corporate structure, we believe that we are well positioned to create value for our shareholders and make a difference in the lives of patients.

For more information, please visit www.theravance.com.

THERAVANCE®, the Cross/Star logo, MEDICINES THAT MAKE A DIFFERENCE® and VIBATIV® are registered trademarks of the Theravance Biopharma group of companies. Trademarks, trade names or service marks of other companies appearing on this press release are the property of their respective owners.

This press release contains and the conference call will contain certain "forward-looking" statements as that term is defined in the Private Securities Litigation Reform Act of 1995 regarding, among other things, statements relating to goals, plans, objectives, expectations and future events. Theravance Biopharma intends such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995. Examples of such statements include statements relating to: the Company's strategies, plans and objectives, the Company's guidance regarding revenue and U.S. net sales related to VIBATIV and non-GAAP operating losses, the Company's regulatory strategies and timing of clinical studies, the potential benefits and mechanisms of action of the Company's product and product candidates, the Company's expectations for product candidates through development and commercialization (including their potential as components of combination therapies). These statements are based on the current estimates and assumptions of the management of Theravance Biopharma as of the date of the press release and the conference call and are subject to risks, uncertainties, changes in circumstances, assumptions and other factors that may cause the actual results of Theravance Biopharma to be materially different from those reflected in the forward-looking statements. Important factors that could cause actual results to differ materially from those indicated by such forward-looking statements include, among others, risks related to: delays or difficulties in commencing or completing clinical studies, the potential that results from clinical or non-clinical studies indicate the Company's product candidates are unsafe or ineffective (including when our product candidates are studied in combination with other compounds), the feasibility of undertaking future clinical trials for our product candidates based on FDA policies and feedback, dependence on third parties to conduct clinical studies, delays or failure to achieve and maintain regulatory approvals for product candidates, risks of collaborating with third parties to discover, develop and commercialize products, risks associated with establishing and maintaining sales, marketing and distribution capabilities with appropriate technical expertise and supporting infrastructure and risks of developing an institutional customer mix for VIBATIV that meet the Company's plan for the product. Other risks affecting Theravance Biopharma are described under the heading "Risk Factors" contained in Theravance Biopharma's Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission (SEC) on May 13, 2015, under the heading "Risk Factors" contained in the Form S-3 Registration Statement filed by Theravance Biopharma with the SEC on July 9, 2015, and Theravance Biopharma's other filings with the SEC. In addition to the risks described above and in Theravance Biopharma's filings with the SEC, other unknown or unpredictable factors also could affect Theravance Biopharma's results. No forward-looking statements can be guaranteed and actual results may differ materially from such statements. Given these uncertainties, you should not place undue reliance on these forward-looking statements. Theravance Biopharma assumes no obligation to update its forward-looking statements on account of new information, future events or otherwise, except as required by law.


                         THERAVANCE BIOPHARMA, INC.
               CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
                                 (Unaudited)
                    (In thousands, except per share data)

                                  Three Months Ended     Six Months Ended
                                        June 30,              June 30,
                                 --------------------- ---------------------
                                    2015       2014       2015       2014
                                 ---------- ---------- ---------- ----------
Revenue:
 Product sales                   $   2,124  $     861  $   3,404  $   1,806
 Revenue from collaborative
  arrangements                       5,010      2,113     24,131      2,113
                                 ---------- ---------- ---------- ----------
  Total revenue                      7,134      2,974     27,535      3,919

Costs and expenses:
 Cost of goods sold                    505        279        875        467
 Research and development (1)       30,377     46,283     66,396     88,006
 Selling, general and
  administrative (1)                21,545     13,118     43,293     32,170
                                 ---------- ---------- ---------- ----------
  Total costs and expenses          52,427     59,680    110,564    120,643
                                 ---------- ---------- ---------- ----------

Loss from operations               (45,293)   (56,706)   (83,029)  (116,724)
Interest and other income              204        214        414        214
                                 ---------- ---------- ---------- ----------
Loss before income taxes           (45,089)   (56,492)   (82,615)  (116,510)
Provision for income taxes           2,514      1,723      7,463      1,723
                                 ---------- ---------- ---------- ----------
Net loss                         $ (47,603) $ (58,215) $ (90,078) $(118,233)
                                 ========== ========== ========== ==========

Net loss per share:
 Basic and diluted net loss per
  share                          $   (1.42) $   (1.83) $   (2.71) $   (3.72)
                                 ========== ========== ========== ==========
 Shares used to compute basic
  and diluted net loss per share    33,532     31,768     33,183     31,768
                                 ---------- ---------- ---------- ----------

1.  Amounts include share-based compensation expense as follows :


                                               Three Months     Six Months
                                              Ended June 30,  Ended June 30,
                                             --------------- ---------------
(In thousands)                                 2015    2014    2015    2014
-------------------------------------------- ------- ------- ------- -------
Research and development                     $ 6,817 $ 4,194 $14,299 $ 8,914
Selling, general and administrative            7,845   2,570  15,989  10,550
                                             ------- ------- ------- -------
 Total share-based compensation expense      $14,662 $ 6,764 $30,288 $19,464
                                             ======= ======= ======= =======


                         THERAVANCE BIOPHARMA, INC.
                    CONDENSED CONSOLIDATED BALANCE SHEETS
                    (In thousands, except per share data)

                                         June 30,           December 31,
                                           2015                 2014
                                   -------------------- --------------------
Assets                                  (Unaudited)              (1)
Current assets:
  Cash and cash equivalents and
   marketable securities           $            228,780 $            306,010
  Receivables from collaborative
   arrangements (2)                              25,488                1,840
  Prepaid and other current assets               11,199                6,373
  Inventories                                    12,553               12,546
Restricted cash                                     833                  833
Property and equipment, net                       9,609                9,663
Other assets                                      1,017                  506
                                   -------------------- --------------------
  Total assets                     $            289,479 $            337,771
                                   ==================== ====================

Liabilities and Shareholders'
 Equity:
Current liabilities (3)            $             24,477 $             41,256
Long-term Liabilities                             7,328                6,728
Shareholders' equity                            257,674              289,787
                                   -------------------- --------------------
  Total liabilities and
   shareholders' equity            $            289,479 $            337,771
                                   ==================== ====================

Note 1: The condensed consolidated balance sheet at December 31, 2014 has been derived from the audited consolidated financial statements at that date included in the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2014.

Note 2: Receivables from collaborative arrangements at June 30, 2015 includes $23.0 million in receivables associated with Mylan collaboration.

Note 3: Amounts include the current portion of deferred revenue of $0.3 million and $0.1 million as June 30, 2015 and December 31, 2014.

Contact Information:

Renee Gala
Chief Financial Officer
650-808-4045
investor.relations@theravance.com